Early life and education
Lee graduated with a B.E. degree inCareer
Following his postdoctoral training, Lee joined Purdue University as an assistant professor in 2015, and became Leslie A. Geddes Assistant Professor in 2020, and Leslie A. Geddes Associate Professor in 2021. Since 2021, he has been serving as Industry Advisory Board (IAB) Professor at Hanyang University. Lee has been appointed as a scientific advisor for Omniply Technologies since 2018; as chief technical officer (CTO) of Rescue Biomedical, since 2019; and has also served as chief technical officer (CTO) of Curasis from 2018 to 2021. He developed and led an international dual MS degree program in the Weldon School of Biomedical Engineering and the School of Mechanical Engineering at Purdue University withResearch
Lee's research is focused on the development of wearable biomedical devices, with particular attention on the scalable production of stretchable sensors in quantities required for clinical testing, and ultimately widespread applications.Clinical and healthcare practices
Lee has made significant contribution towards the development of a skin sensor patch tailored for various human body parts in order to detect clinically important biosignals in real time. Lee is also a pioneer in the development of a soft patch featured with miniaturized functional needles for applications involving intracellular delivery of biomolecules as well as intracellular recording of electrophysiological signals at the cellular scale. He designed these devices to enable placement of the needles at characteristic dimensions equivalent to those of human cells, as well as provide the basis for interactions with the surrounding tissue defined by these cells.Wearable biomedical technology
Lee along with his team also works to develop wearable technology for animals by enabling direct printing of functional nanomaterials into textile weave of commercial blankets for animals over large scale. Lee has teamed up with Laurent Couetil in Purdue Veterinary Medicine to develop a smart connected blanket for horse with asthma in order to monitor respiration rate continuously, or even overnight, from a distance. These devices were made possible by the discovery and development of transfer printing of thin film electronics by Lee and his colleagues. Lee's method prints a nearly infinite number of thin film electronics on a single wafer, which are then delaminated from the wafer using simply water. The thin film electronics are then placed and bonded on elastic surfaces to form flexible devices.Drug delivery systems
In 2022, Lee introduced a new concept of drug delivery system using a combination of silicon nanoneedles and a tear-soluble contact lens, enabling the painless and long-term sustained release of ocular drugs into eyes. Lee teamed up with Yanni Paulus in the University of Michigan Medicine to demonstrate the utility of the drug delivery system in effectively treating a chronic ocular disease, such as corneal neovascularization, in a rabbit model without showing a noticeable side effect over current standard therapies. In his early works, Lee introduced a wirelessly operated, implantable drug delivery system using a combination of thermally actuated lipid membranes embedded with multiple types of drugs. He also discussed underlying operational and materials aspects, as well as the basic efficacy and biocompatibility of the system. In another study, he presented a system in which the constituent materials undergo complete bioresorption to eliminate device load from the patient after completing the final stage of the release process. He demonstrated the applications of this technology in terms of the treatment of cancerous tissues by release of the drug doxorubicin. Moreover, he presented a review on the emerging trends and latest innovations of wearable glucose monitoring and implantable insulin delivery technologies for diabetes management with a focus on their advanced materials and construction.Awards and honors
*2013 – Graduate Student Silver Award,Bibliography
*M. Kim*, C. Kantarcigil*, B. Kim, R. K. Baruah, S. Maity, Y. Park, K. Kim, S. Lee, J. B. Malandraki, A. Avlani, A. Smith, S. Sen, M. A. Alam, G. Malandraki*, C. H. Lee*, Flexible submental sensor patch with remote monitoring controls for management of oropharyngeal swallowing disorders, Science Advances, 5, 12, eaay3210 (2019). *B. Kim*, M Kim*, Y. Cho, E. Hamed, M. Gillette, H. Cha, N. Miljkovic, V. Aakalu, K. Kang, K. Son, K. Schachtschneider, L. Schook, C. Hu, G. Popescu, W. Balance, S. Yu, S. Im, J. Lee, C. H. Lee*, H. Kong*, Electrothermal soft manipulator enabling rapid transport and assembly of thin biological sheets and electronic devices, Science Advances, 6, 42, eabc5630 (2020). *K. Kim*, H. Kim*, H. Zhang*, W. Park, D. Meyer, M. Kim, B. Kim, H. Park, B. Xu*, P. Kollbaum*, B. Boudouris*, C. H. Lee*, All-printed corneal electrodes on soft contact lenses for noninvasive recording of human electroretinogram, Nature Communications, 12, 1544 (2021) *B. Kim*, A. Soepriatna*, W. Park, H. Moon, A. Cox, J. Zhao, N. Gupta, C. Park, K. Kim, Y. Jeon, H. Jang, D. Kim, H. Lee, K. Lee*, C. Goergen*, C. H. Lee*, Rapid custom printing of poroelastic biosensor for simultaneous epicardial recording and imaging, Nature Communications, 12, 3710 (2021) *T. Chang*, S. Akins*, M. Kim, L. Murray, Y. Park, S. Cho, S. Hur, L. Couetil*, M. Jun*, C. H. Lee*, Programmable dual regime spray for large-scale and custom-designed electronic textiles, Advanced Materials, 34, 9, 2108021 (2022) – Journal Cover FeatureReferences
{{DEFAULTSORT:Lee, Chi Hwan Living people Ajou University alumni Illinois Institute of Technology alumni Stanford University alumni Purdue University faculty Biomedical engineers Year of birth missing (living people)